Exploring a Culture of Learning with Technology: An Ethnographic Content Analysis of the Activity of Learning with Educational iPad Apps

This study explored the culture of learning with educational iPad apps using activity theory as a guiding framework. First, the top nine educational apps were tracked in the Top Charts section of Apple’s App Store for a duration of four months. The nine sampled apps, selected based on their frequency of appearance, included Toca Hair Salon 2, Stack the States, Endless Alphabet, Mickey Mouse Clubhouse: Wildlife Count Along, Wild Kratts Creature Power World Adventure, Wallykazam! Letter and Word Magic, Starfall Learn to Read, Dr. Panda’s Restaurant 2, and Bug Art. The descriptions, version updates, app content, and customer reviews for each app were digitized, coded, and analyzed in Dedoose using the Activity Checklist. Additionally instructional analysis diagrams were developed to provide insight into the user interface and actions. Results of the study were presented in the form of nine portraits. The overview and relevant instructional characteristics were detailed for each app. The final chapter examined the broader implications of the app experience. The technology, the instruction, the adult guide, and the App Store were identified as mediating factors that contributed to the dynamic app culture

Rethinking Trends in Instructional Objectives: Exploring the Alignment of Objectives with Activities and Assessment in Higher Education – A Case Study

This study explored higher education level syllabi to identify trends in educational objectives. Bloom’s Taxonomy and various strategic models were used to classify 714 objectives from 114 sections of courses administered through a Midwest teacher education institution in the United States. 1229 verbs and verb phrases were classified through the Taxonomy and differentiated between higher and lower ordered verbs as well as measureable and non-measureable learning outcomes. The results indicated that though learning outcomes the objectives are suggestive of higher ordered skills although the syllabi do not adequately provide information on the expected outcomes of the course

Reduction of exogenous ketones depends upon NADPH generated photosynthetically in cells of the cyanobacterium Synechococcus PCC 7942

Effective utilization of photosynthetic microorganisms as potential biocatalysts is favorable for the production of useful biomaterials and the reduction of atmospheric CO2. For example, biocatalytic transformations are used in the synthesis of optically active alcohols. We previously found that ketone reduction in cells of the cyanobacterium Synechococcus PCC 7942 is highly enantioselective and remarkably enhanced under light illumination. In this study, the mechanism of light-enhanced ketone reduction was investigated in detail using several inhibitors of photosynthetic electron transport and of enzymes of the Calvin cycle. It is demonstrated that light intensity and photosynthesis inhibitors significantly affect the ketone reduction activity in Synechococcus. This indicates that the reduction correlates well with photosynthetic activity. Moreover, ketone reduction in Synechococcus specifically depends upon NADPH and not NADH. These results also suggest that cyanobacteria have the potential to be utilized as biocatalytic systems for direct usage of light energy in various applications such as syntheses of useful compounds and remediation of environmental pollutants

Spreading of Antarctic Bottom Water examined using the CFC-11 distribution simulated by an eddy-resolving OGCM

We have investigated the spreading and pathway of Antarctic Bottom Water(AABW) using the simulated distribution of chlorofluorocarbons(CFCs) in a global eddy-resolving(1/10°) OGCM. Our goal is understanding of the processes and pathways determining the distribution of CFCs in the Southern Ocean, where much of this tracer is entrained by formation of deep and bottom water. The simu- lated high CFC-11 water reveals the newly formed AABW around the Antarctic Continent. The main source regions of AABW in the model are in the Weddell Sea(60°- 30°W ), offshore of Wilkes Land(120°- 160°E ) and in the Ross Sea(170°E -160°W ). In our model, spreading of simulated CFC-11 in the deep Southern Ocean from the newly formed AABW regions is more similar to the observed distribution than in coarse-resolution models. In the Weddell Sea, the high CFC-11 water spreads eastward with the Antarctic Circumpolar Current(ACC) and flows northward to the Argentine Basin. The high CFC-11 water from Wilkes Land joins with the high CFC-11 water from the Ross Sea. Some of the high CFC-11 water from Wilkes Land flows northward toward New Zealand. The high CFC-11 water from the Ross Sea flows eastward with the ACC along the Mid Ocean Ridge and northward to the Southeast Pacific Basin

Vestibular Compensation after Vestibular Dysfunction Induced by Arsanilic Acid in Mice

When vestibular function is lost, vestibular compensation works for the reacquisition of body balance. For the study of vestibular dysfunction and vestibular compensation, surgical or chemical labyrinthectomy has been performed in various animal species. In the present study, we performed chemical labyrinthectomy using arsanilic acid in mice and investigated the time course of vestibular compensation through behavioral observations and histological studies. The surgical procedures required only paracentesis and storage of 50 μL of p-arsanilic acid sodium salt solution in the tympanic cavity for 5 min. From behavioral observations, vestibular functions were worst at 2 days and recovered by 7 days after surgery. Spontaneous nystagmus appeared at 1 day after surgery with arsanilic acid and disappeared by 2 days. Histological studies revealed specific damage to the vestibular endorgans. In the ipsilateral spinal vestibular nucleus, the medial vestibular nucleus, and the contralateral prepositus hypoglossal nucleus, a substantial number of c-Fos-immunoreactive cells appeared by 1 day after surgery with arsanilic acid, with a maximum increase in number by 2 days and complete disappearance by 7 days. Taken together, these findings indicate that chemical labyrinthectomy with arsanilic acid and the subsequent observation of vestibular compensation is a useful strategy for elucidation of the molecular mechanisms underlying vestibular pathophysiologies

アルサニル酸を用いたマウス内耳破壊後の前庭代償過程

When vestibular function is lost, vestibular compensation works for the reacquisition of body balance. For the study of vestibular dysfunction and vestibular compensation, surgical or chemical labyrinthectomy has been performed in various animal species. In the present study, we performed chemical labyrinthectomy using arsanilic acid in mice and investigated the time course of vestibular compensation through behavioral observations and histological studies. The surgical procedures required only paracentesis and storage of 50 µL of p-arsanilic acid sodium salt solution in the tympanic cavity for 5 min. From behavioral observations, vestibular functions were worst at 2 days and recovered by 7 days after surgery. Spontaneous nystagmus appeared at 1 day after surgery with arsanilic acid and disappeared by 2 days. Histological studies revealed specific damage to the vestibular endorgans. In the ipsilateral spinal vestibular nucleus, the medial vestibular nucleus, and the contralateral prepositus hypoglossal nucleus, a substantial number of c-Fos-immunoreactive cells appeared by 1 day after surgery with arsanilic acid, with a maximum increase in number by 2 days and complete disappearance by 7 days. Taken together, these findings indicate that chemical labyrinthectomy with arsanilic acid and the subsequent observation of vestibular compensation is a useful strategy for elucidation of the molecular mechanisms underlying vestibular pathophysiologies.博士（医学）・甲第742号・令和2年3月16日© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)

Big Three Dragons: A [N II] 122 μ\mum Constraint and New Dust-continuum Detection of A z=7.15z = 7.15 Bright Lyman Break Galaxy with ALMA

We present new Atacama Large Millimeter/submillimeter Array Band 7 observational results of a Lyman break galaxy at $z=7.15$, B14-65666 ("Big Three Dragons"), which is an object detected in [OIII] 88 $\rm{\mu m}$, [CII] 158 $\rm{\mu m}$, and dust-continuum emission during the epoch of reionization. Our targets are the [NII] 122 $\rm{\mu m}$ fine-structure emission line and underlying 120 $\rm{\mu m}$ dust continuum. The dust continuum is detected with a $\sim$19$\sigma$ significance. From far-infrared spectral energy distribution sampled at 90, 120, and 160 $\rm{\mu m}$, we obtaine a best-fit dust temperature of $40$ K ($79$ K) and an infrared luminosity of $\log_{10}(L_{\rm IR}/{\rm L}_\odot)=11.6$ ($12.1$) at the emissivity index $\beta = 2.0$ (1.0). The [NII] 122 $\rm{\mu m}$ line is not detected. The 3$\sigma$ upper limit of the [NII] luminosity is $8.1 \times 10^7\ {\rm L}_\odot$. From the [NII], [OIII], and [CII] line luminosities, we use the Cloudy photoionization code to estimate nebular parameters as functions of metallicity. If the metallicity of the galaxy is high ($Z > 0.4\ {\rm Z}_\odot$), the ionization parameter and hydrogen density are $\log_{10} U \simeq -2.7\pm0.1$ and $n_\text{H} \simeq 50$-$250\ {\rm cm}^{-3}$, respectively, which are comparable to those measured in low-redshift galaxies. The nitrogen-to-oxygen abundance ratio, $\rm{N/O}$, is constrained to be sub-solar. At $Z < 0.4\ {\rm Z}_\odot$, the allowed $U$ drastically increases as the assumed metallicity decreases. For high ionization parameters, the $\rm{N/O}$ constraint becomes weak. Finally, our Cloudy models predict the location of B14-65666 on the BPT diagram, thereby allowing a comparison with low-redshift galaxies.Comment: 17 pages, 13 figures, 2 tables. accepted for publication in Ap